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When You Might Need Higher B12 Doses While the standard RNI of 1.5 mcg per day suffices for most healthy adults, certain medical conditions, dietary patterns, and medications can substantially increase B12 requirements or impair absorption, necessitating higher therapeutic doses under medical supervision

There are different forms of B12 available in supplement form including cyanocobalamin, methylcobalamin and hydroxocobalamin that for the most part are believed to be equally effective

Clinicians therefore combine general wound care principles and nursing experience to form practical advice