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This is an Amadori-rearrangement (fructosamine) building block in which valine is modified with a fructose-derived adduct
supporting use as a cell-permeable precursor or as a synthetic intermediate
bioavailability studies
4-Methylumbelliferyl (MU) glycosides are fluorogenic enzyme substrates: cleavage of the glycosidic bond by the target enzyme releases free 4-methylumbelliferone
GP100110: Arg8-CGSG-MUC1(137-156)-Tn(144) Pack Size:0.5 mg This is an Amadori-rearrangement (fructosamine)C146H253N63O45S 3643. 03 MUC1 (UniProt ID P15941) synthetic glycopeptide fragment (Gly137 His156; UniProt position 137 156, aa length 20) from the variable number tandem repeat (TR) domain. The fragment contains tumour associated carbohydrate antigen (TACA), Tn (GalNAc O Thr) at Thr144. Arg8 is conjugated at N terminal. Arg8 is separated from the MUC1 sequence by Cys Gly Ser Gly. The C terminus is an amide. Arg8 CGSG MUC1(137 156) Tn(144) Mucin1; R8
