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Correlation between AGEs and feature of PCOS PCOS has been defined as a disorder due to an excess of androgens and insulin resistance, about 5070% of women with PCOS have a certain degree of resistance to insulin, which is defined as a state in which more insulin is required than the normal to obtain an appropriate response [47]

That broad activation produces muscle growth alongside acne, hair loss, liver strain, cardiovascular stress, and hormonal shutdown (Basaria et al., NEJM 2010)

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