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That puts retatrutide essentially on a par with bariatric surgery, says Daniel Drucker, a university professor of medicine at the University of Toronto, who has previously consulted for Eli Lilly but was not involved in the trial

Injectable semaglutide has a half-life of approximately 7 days, while tirzepatide lasts roughly 5 days, meaning the drug concentration drops by half during these periods

However, it is not entirely certain how many of these patients met ME/CFS criteria, suggesting that replication studies should be done in future to help us understand the genes, cellular processes, and tissues or cells that causally change the risk for developing ME/CFS

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