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Medications That May Interact With Retatrutide Retatrutide's effect on gastric emptying can delay absorption of oral medicines including warfarin, levothyroxine, and antiepileptics

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The Food and Drug Administration (FDA) only approved Wegovy (semiglutide) as a chronic weight management drug for the obese and overweight in 2021, followed by Mounjaro and Zepbound (both tirzepatides) in 2022 and 2023