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This review will discuss the various therapeutic techniques being developed from each level of the central dogma with examples including: CRISPR activation (CRISPRa) and gene replacement at the DNA level, antisense oligonucleotides (ASOs) at the mRNA level, and small-molecule drugs at the protein level, followed by a review of current delivery methods for these therapeutics

Furthermore, some studies have demonstrated that glutamate can fuel the TCA cycle via an anaplerotic reaction of the TCA cycle intermediate -ketoglutarate, which contributes to redox balance and increase NADH production for the proliferation of cancer cells (59, 60)

Specifically , it plays a major role in forming red blood cells and keeping the nervous system healthy

The neuropathology of alcohol-related brain damage