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(1997) 273:E9818

(A) Fear Conditioning Memory Test results, with the HFD SEMA group demonstrating significantly better learning and memory retention, indicated by a longer hesitation time before stepping onto the electrified grid, compared to the untreated HFD group

The absence of glucose effects means dosing does not need to be coordinated with meals or adjusted for diabetic status, and there are no concerns about timing relative to insulin sensitivity

Current evidence suggests that dapagliflozin may elevate the risk of bladder and breast cancers, whereas other SGLT2 inhibitors have not demonstrated such associations [10]