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Human organs-on-chips for disease modelling, drug development and personalized medicine

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To address organelle-specific pH and redox environments, turn-on zinc fluorescent probes (ZnDA-2H and ZnDA-3H) with low pH sensitivity and high affinity were developed and targeted to the cytosol, nucleus, ER and mitochondria using HaloTag technology, enabling the precise quantification of labile zinc distribution 189

"Effects of bedtime administration of zolpidem on sleep/wake cycle in healthy elderly volunteers." Journal of Clinical Pharmacology 35.11 (1995): 1092-1097