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More practical contributors to heart rate increases, especially early in therapy, may include volume depletion from gastrointestinal side effects such as nausea, vomiting, and diarrhea, which are common during GLP-1 receptor agonist initiation

If at any point you feel the onset of a headache, increased nervousness or agitation, irritability, or overstimulation, immediately stop and spit out any remaining lozenge in your mouth