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4.29.19 Holly said: Hi Dr

It has been demonstrated that silibinin treatment reduces ROS production in Kupffer cells (with a 50% inhibition concentration of 80 mol/L) (Conde de la Rosa et al., 2022)

The effect on mitochondria is supported by pretreatment of pancreatic -cells with micromolar concentrations of acetylcarnitine, which protected the cells from oleic acid-induced mitochondrial dysfunction and decreasing ROS production [120]