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(270) reported a patient in whom clinical, laboratory and histologic features of autoimmune hepatitis developed after beginning MEL therapy for the treatment of insomnia

These cells release common neurotransmitters such as gamma aminobutyric acid (GABA), serotonin (5-HT) and noradrenaline upon depolarization via voltage gated Ca 2+ channels [2540]

Selank, built from an immune peptide, is framed as an anxiolytic that tunes GABA and serotonin signaling without the sedation or dependence of benzodiazepines, which is why its flagship Russian trial targeted generalized anxiety