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[23] In one study, when NAC was added to rat bone marrow cultures, significant improvements were seen in the activity of alkaline phosphatase (levels of which increase when bones are growing) and osteoblastic cultures (cells that develop bone), as well as an upregulation of bone-related gene markers such as collagen
This might especially be the case at low rates of ascorbate oxidation, which will probably entail low accumulation of MDHA and low rates of DHA formation (Tuzet et al
Miraglia and Colla, 2019
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