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[22] [23] Pioglitazone , a diabetes medication, has also shown benefit in some patients with biopsy-proven NASH, but its use should be specialist-supervised and limited to selected cases

Natural Alternatives and Adjunctive Support with Botanicals and Nutrients Certain nutrients and botanicals have demonstrated GLP-1 agonist activity, and are not associated with the complications often seen with pharmaceutical GLP-1 drug use