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Dietary fiber, protein-rich foods, and polyphenol-rich plants can enhance endogenous GLP-1 secretion from intestinal L-cells, creating measurable metabolic effects in some individuals

Looking forward, federal developments could shift states back toward coverage: the November 2025 announcement of most-favored-nation pricing and CMSs BALANCE model will likely make these drugs more affordable for state Medicaid programs, potentially improving short-term cost-effectiveness

While mild to moderate bloating is a common and generally manageable side effect of semaglutide, certain symptoms warrant prompt medical evaluation

Among 111,104 SGLT2 inhibitor users who were alive 1 year after the date of filling their first prescription, 64% had 80% of proportion of days covered, 58% had 90% proportion of days covered, and 33% had 100% proportion of days covered