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The best non-diabetic body-composition anchor favors tirzepatide, about 75:25 fat-to-lean loss in its DXA data versus about 62:38 in semaglutides. This is cross-trial evidence, not a head-to-head maintenance-dose DXA result
Moreover, increased vitamin B6 levels are required during pregnancy and breastfeeding to support the developing babys brain and nervous system
Semaglutide (Wegovy) is FDA-approved for chronic weight management (with criteria) and has strong clinical trial evidence for meaningful average weight loss when paired with lifestyle support
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