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intravenous TB-4 Phase 1 safety and pharmacokinetics, no dose-limiting or serious adverse events (Ann N Y Acad Sci 2010;1194:223229): NCT00743769 Centers for Disease Control and Prevention

The vitamin does not interact with serotonin receptors, dopamine receptors, or other pathways targeted by proven anti-nausea medications

Even with b12 deficiency, this pathway continues functioning at reduced efficiency rather than stopping completely

Tissue repair depends on diagnosis, blood flow, inflammation, sleep, protein intake, micronutrients, load management, rehabilitation, hormones, metabolic health, medications, and time