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Additionally, reduced sodium intake associated with healthier eating patterns may decrease fluid retention, leading to increased urination as excess fluid is eliminated

2024 Meta-Analysis Indicates That GLP-1RAs Reduce Adverse CV Events A 2024 Meta-analysis of 13 multiple cardiovascular outcome trials has documented that GLP1-RA therapy significantly reduces the risk of major adverse cardiovascular events (MACEs), all-cause mortality, CV mortality, stroke, risk for coronary revascularization, and composite adverse kidney outcomes in both sexes, regardless of a patient's history of cardiovascular disease, BMI or eGFR (Rivera et al, 2024)

Injection Site Rotation Both subcutaneous and intramuscular injection sites should be rotated systematically to prevent lipodystrophy (SubQ) or localized fibrosis (IM)

doi: 10.1006/bbrc.1994.1246