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In order to replenish GSH, GSSG is reduced back to GSH by glutathione reductase

[DOI] [PubMed] [Google Scholar] 8.Nowell J., Blunt E., Edison P

In contrast, M2-type macrophages demonstrate enhanced iron efflux capacity through higher ferroportin (FPN) expression and lower FT levels, inducing elevated CD91 or CD163 expression (79)