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10.1097/HJH.000000000000348037345492 110 Virdis A, Masi S, Casiglia E, et al

RUNX2 binds to the promoter of the Prx2 encoding gene and enhances the transcription, thereby decreasing vulnerability towards ferroptosis [154]

Leoncini, G

The current findings disagree with Wantanable and colleagues , who observed a good evidence favoring efficacy of topical oxidized glutathione 2% lotion when applied twice daily for 10 weeks in producing skin whitening and also statistically significant reduction of skin melanin index by using Mexameter (a tool objectively measures melanin index of the skin) compared with placebo