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In neuroblastoma cells, Epitalon reduced levels of 8-hydroxydeoxyguanosine (8-OHdG), a key marker of oxidative DNA damage that accumulates in aging neurons and is elevated in Alzheimers and Parkinsons disease [51]
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The reaction time was defined by placing the mouse on the hot plate, and the time was recorded when the animal showed hind paw licking or jumping, and the 45 sec period was observed to avoid tissue damage
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They amplify results through complementary cellular actions rather than replacing these conventional approaches
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