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Research suggests that receptor response may begin to decline after 6-8 weeks of continuous exposure, though the degree and time course vary among people and tissue types

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At peripheral levels, the administration of GLP-1 RA regulates follicular proliferation and apoptosis-induced follicular atresia of the granulosa cells, a key component of the dominant follicle selection, possibly contributing to the oocyte maturation in PCOS

In summary, eating behaviors are influenced by a range of biological, psychological, and genetic factors, with disruptions contributing to disorders like binge eating