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10.1016/j.cardfail.2017.04.014 119 YoshidaY.ShimizuI.ShimadaA.NakaharaK.YanagisawaS.KuboM.et al (2022)

Therapeutic strategies, including ROS amplification, inhibition of the antioxidant system, and induction of ferroptosis, are discussed as promising approaches for selectively targeting cancer cells

Figure 1 Evidence-based effects of key nutrients After understanding the pathological connection between nutrients and OA and discovering the significant role of the metabolism-inflammation-oxidative stress network in it, this study explores key nutrients that can prevent or treat OA through evidence-based medicine and reveals the mechanisms by which they exert preventive or therapeutic effects (Table 1)

Hydrolysis breaks peptide bonds through water interaction