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Vitamin B6 Why it matters: Vitamin B6 is a cofactor in more than 140 reactions, including those that regulate protein, fat, and glucose metabolism

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The combination of BSO+L-PAM achieved synergistic cytotoxicity (combination index number (CIN) 0.7) and induced 24 logs of cell kill in all nine MM cell lines including the eight lines established at progressive disease (PD) after therapy (U266, OPM-2, NCI H929, KMS-12-PE, EJM, TX-MM-030h, MM.1S and MOLP-2), 25 which include lines with cytogenetic profiles associated with a poor prognosis (Figure 1b)