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The first -glucan mediating step might be immunostimulation, i.e., binding the dietary fiber to the specific receptors in macrophages and dendritic cells, which induces the production of various cytokines and thus activates other immune cells such as T and B cells

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A second group of innate lymphoid cells (ILC2s) has a key role in type II immune response

In particular, the PI3K/AKT axis converts phosphatidylinositol-4,5-bisphosphate (PIP 2 ) to phosphatidylinositol 3,4,5-trisphosphate (PIP 3 )