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These modifications make it approximately 3 times more potent and extend its half-life (20-30 hours) and duration of action

A retrospective study of 94 people using compounded semaglutide with cyanocobalamin showed an average loss of 2.7 kg of fat mass and 1.4 kg of lean mass after three months, compared with prospective studies of brand-name semaglutide, which showed approximately 10 kg of fat mass loss at seven months

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In the majority of cases, people with elevated B12 feel completely normal, and the finding only appears on routine blood work