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Dulaglutide, liraglutide and subcutaneous semaglutide have been approved for reducing the risk of major adverse cardiovascular events in adults with type 2 diabetes mellitus with established cardiovascular disease, dulaglutide is approved for use in type 2 diabetes mellitus with multiple risk factors, and both liraglutide and semaglutide have been approved for chronic weight management

Quality Comparison Tirzepatide Research Overview Tirzepatide is a synthetic dual-agonist peptide designed to interact with both GLP-1 and GIP receptors

GLP-1 agonists are generally well tolerated with GI side effects such as nausea, vomiting, and diarrhea predominating

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