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Three- and six-weeks post infection, respectively, for juvenile and adult worms, mice were treated depending on their weight with formulations of the compounds, while the control mice received only the vehicle

The integrated dataset was then clustered, and highly upregulated genes in each cluster (identified by the Wilcoxon rank sum test in Seurat), along with the spatial context of the clusters location in situ, were used to annotate the predominant cell type in each spot

The great variability of GSTs co-substrates is reflected in the different H-sites shapes and chemical characters found among classes