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It makes it possible to dream that type 2 diabetes could be treated to the point of complete normalisation' (Holst 2024)

Whilst oral bioavailability is relatively poor (less than 5% reaches systemic circulation due to extensive first-pass metabolism), sufficient absorption occurs to produce measurable pharmacological effects in research settings

3 Although several factors contributed to this rise in interest, two key developments have been particularly important: Celebrity endorsement: A number of high-profile celebrities, such as Elon Musk, have publicly credited GLP-1RA drugs with their transformative weight loss, leading to a spike in public interest in using the drugs for weight loss

The review will include an assessment of the affordability of GLP-1, said the health departments deputy director-general for primary healthcare, Jeanette Hunter