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Description

The activation of hGPX4-C by compound 102 were remarkably reduced for mutant D23A (the compound concentration required to reach 150% activation was higher than 2,500 M)

Disclaimer: This information reflects findings from preclinical and observational research

TMPRSS2 contributes to virus spread and immunopathology in the airways of murine models after coronavirus infection

Results Univariate analysis revealed significantly elevated levels of alpha-ketoglutarate (aKG) and reduced levels of creatine in patients with Long COVID