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While there are several reports suggesting that the BBB shows disruption in ALS [131133], the studies mentioned above indicate that transplantation of monocytes/microglia might require additional conditioning of patients for optimal recruitment and engraftment

Glutathione and Vitamin C are commonly taken together because Vitamin C helps improve glutathione activity and antioxidant support in the body

Similarly, epigallocatechin, a naturally occurring antioxidant present in fruits, nuts, and tea, inhibited oxidative stress, induced motor neuron degeneration, and prolonged survival of SOD1 G93A mice (Koh et al., 2004, 2006

35 , e2206821 (2023)