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Due to the variability in skin phenotypes, extra-cutaneous symptoms, and disease progression among patients, it is posited that many genes arising from linkage disequilibrium contribute to the pathogenesis of psoriasis (Hugh and Weinberg 2018)

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The average out-of-pocket cost for GLP-1 medications ranges from $900 to $1,200 per month without insurance coverage, while in-network costs for patients with insurance can vary significantly, often falling between $25 to $200 per month, depending on the plan and copay assistance programs