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Expression of genes related to mitochondrial and peroxisomal -oxidation was higher in patients with more severe steatosis ( n = 11) compared to patients with less severe steatosis ( n = 21) or non-steatotic controls ( n = 16) [96]

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There is one open-label intravenous safety pilot in two healthy adults, who received single doses of 10 mg and 20 mg with no comparator, no blinding, and short-term observation limited to vital signs, self reported symptoms and labs across two days [4]

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