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In conclusion, the repolarization of tumor-promoting M2 TAMs to M1-type TAMs that kills tumors is a major strategy to reverse immunosuppressive TME to anti-tumor TME by influencing TAMs, and a variety of nanodrug delivery systems have been developed, such as iron-based nanoparticles, nanoparticles loaded with TLR agonists, and nanoparticles loaded with signaling pathway inhibitors or activators

It can also come in several sizes as determined by the doctor, starting from 0.07 - 2 millimeters

It tends to upregulate genes involved in regeneration and downregulate those associated with inflammation or fibrosis

2003 [cited 2024 Jan 27];29:22330