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Fernandez recommends avoiding glycolic acid under the following circumstances: Avoid using too many glycolic acid-containing products at the same time Do not use it if you have recently had microdermabrasion or any treatment that removes the top layer of your skin Discontinue use while being at the beach or exposed to the sun Do not combine it with other acne medication or cosmetics before consulting with your dermatologist Do not use it at the same time as any laser treatments Always use sunscreen when using glycolic acid If you wish to become pregnant, are pregnant or are breastfeeding, always consult your doctor before applying cosmetic products

J Mol Cell Cardiol 114:220233 Kaprielian R, del Monte F, Hajjar RJ (2002) Targeting Ca2+ cycling proteins and the action potential in heart failure by gene transfer

Those numbers should give any serious researcher pause

individual biology, trial quality and treatment duration all matter