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Clinical assessment should include a thorough history and examination to exclude other causes of persistent hiccups, such as gastro-oesophageal reflux disease (GORD), gastric distension, central nervous system pathology, metabolic disturbances, or medication interactions

497 A metaanalysis reported that caregivers of people living with dementia were significantly more likely to experience depression and anxiety than noncaregivers

FIGURE 2 The genus Akkermansia is consistently enriched in human PD patients versus healthy controls, and the data corroborate recent findings in an A53T -synuclein Tg non-human primate model