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Some users may notice initial improvements in energy levels and recovery within a few weeks, while more significant changes in muscle growth, fat loss, and overall body composition may take several months of consistent use

then weekly injections in the following month, and finally monthly injections after that

More seriously, they are contraindicated in patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (MEN2), and they must be used carefully in patients with a history of pancreatitis or certain gallbladder conditions

The most characteristic feature of pSS is focal lymphocytic sialadenitis (FLS), which is used in the classification of pSS (3)