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This finding was replicated in nonhuman primates using another antibody, now against the human GIP receptor, supportive of an antagonistic approach for obesity treatment (54)

Consistency comes first

The sensation is typically mild to moderate, described as a dull pressure rather than a sharp pain

Hence an approval in the next one-and-a-half to two years seems unlikely." Chereddi adds, "Hengrui's product is just starting Phase 3 in China, and Innovent's product has approval from the Chinese FDA, but hasn't been filed in India." His conclusion: "Indian generic manufacturers face a limited but real opportunitynot an open market." Shah frames it as a "timing risk, not an inevitability", and flags three gating factors beyond trial requirements: Regulatory scrutiny of novel oral delivery systems, bioavailability concerns specific to Indian populations and intellectual property protection on oral peptide platforms that limits immediate generic replication