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Always defer to manufacturer recommendations when available

The guidance, published in the Annals of Internal Medicine, alongside a patient summary, is designed to help physicians navigate the rapidly evolving landscape of obesity medications

they meaningfully alter appetite, gastric emptying, and body composition. He continued, The biggest risk I see is applying data from patients with obesity or metabolic disease to populations where we dont have good evidence, namely, lean patients, cosmetic use, or medically complex individuals

Hydration-first strategy when dryness/irritation parallels nausea/vomiting/diarrhoea: reinforce regulator-labelled dehydration precautions