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10.1016/j.freeradbiomed.2013.09.009 2 AjoolabadyA.AslkhodapasandhokmabadH.ZhouY.RenJ

Fatty acids with a higher number of double bonds are more susceptible to this process, as the removal of hydrogen atoms becomes easier with increased unsaturation

However, dietary intake is estimated at only 12 mg per day from a typical mixed diet far below the therapeutic doses used in clinical studies (3001,800 mg/day) [1][2]