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Carrageenan-Induced Paw Edema (Preliminary Data) Carrageenan-induced paw edema was performed as previously indicated by a subplantar injection of carrageenan (0.1 mL/rat of a 1% suspension in saline) (Sigma-Aldrich, Milan, Italy) into the right hind paw [44]

In addition to neurological symptoms, fatigue is reported by most patients with MS and is associated with a poor quality of life [56]

Evidence from experimental in vitro models indicates that cannabinoids modulate facets of both innate and adaptive immunity, many of which are immunosuppressive, and this could be beneficial in certain scenarios but detrimental in others

Gunesch S, Hoffmann M, Kiermeier C, Fischer W, Pinto AFM, Maurice T, Maher P, Decker M (2020) 7-O-Esters of taxifolin with pronounced and overadditive effects in neuroprotection, anti-neuroinflammation, and amelioration of short-term memory impairment in vivo