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Interestingly, supplementation of metformin with 1.5 mg dulaglutide per week in the treatment of T2MD in obese patients with severe impairment of glycosylated hemoglobin A1c (HbA1c) was reported to bring lasting benefits in the control of glucose metabolism and body weight (173)

The fat loss it produces may be measurable in clinical settings but is unlikely to produce the kind of visible, health-altering transformation that tirzepatide delivers

Retatrutide fans say it helps you shred fat and gives you energy to build muscle

This mirrors the maintenance dosing strategy being explored with tirzepatide and other medications