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Description

Figure 1 As shown in Figure 2A , chronic metformin treatment decreases insulin levels in the MSG-metformin rats

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Interestingly, in a mouse model of hypoxia-driven PE, replenishment of whole-body NAD + stores via nicotinamide (NAM) treatment has been shown to rescue several PE-like features (i.e., hypertension, fetal growth restriction) (37, 38)

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