semaglutide before pregnancy and Conception: Safety, Timing & Planning Semaglutide and Pregnancy: Safety Guide

The dose escalation schedules differ between the two medications: Semaglutide Dose Escalation Weeks 14: 0.25mg weekly (initiation dose) Weeks 58: 0.5mg weekly Weeks 912: 1.0mg weekly Weeks 1316: 1.7mg weekly Week 17+: 2.4mg weekly (maintenance dose for weight loss) Tirzepatide Dose Escalation Weeks 14: 2.5mg weekly (initiation dose) Weeks 58: 5mg weekly Weeks 912: 7.5mg weekly (many patients maintain here) Weeks 1316: 10mg weekly Weeks 1720: 12.5mg weekly Week 21+: 15mg weekly (maximum dose) Not every patient needs to reach the maximum dose and at BlueWater Wellness Center, we don't escalate for the sake of it

Furthermore, lower concentrations of DPP-IV are inversely associated with increased disease activity, although is not clear whether this is the cause or consequence of disease

Most side effects are gastrointestinal and occur during the early weeks of treatment or when the dose is increased

6 Your GP can recheck HbA1c 3 to 6 months after a significant weight change