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The paradigm for treating people with obesity has often been to recommend lifestyle changes, and then if they develop diabetes or another metabolic condition, to treat them with metformin, insulin, or GLP-1 drugs, says study senior and corresponding author Andrew Stokes, associate professor of global health

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You've been doing this for 30 years, and I think one of the probably biggest changes that have happened over the time that you've been working on obesity is that we've come to see obesity as a chronic recurring disease