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The copper complex is naturally present in human plasma, wound fluid, and saliva, where it promotes wound healing, modulates inflammatory responses, and stimulates production of collagen, elastin, and glycosaminoglycans

DPP-IV inhibitors have shown promise in modulating the immune response, particularly by enhancing T-cell function

MIRENA is also estrogen-free

Of note, a growing number of studies support mitochondrial metabolism of LAC as a common culprit underlying psychiatric and neurodegenerative diseases such as MDD and AD as well as obesity, making it important to further understand mechanisms for the development of aberrant mitochondrial metabolism of LAC