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Further, targeted metabolomics results revealed that GGCT knockdown markedly attenuated TCA cycle flux, decreasing key intermediates including pyruvate, succinate and fumarate (Fig

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Monitoring and Red Flags During Treatment While taking semaglutide, watch for warning signs that warrant immediate contact with your doctor: severe upper abdominal pain radiating to the back, persistent nausea or vomiting, yellowing of skin or eyes (suggesting bile duct involvement), or unexplained elevation in pancreatic enzymes