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Mark Gilbert, a nutritionist at PortionIQ, a science-led range of GLP-1 friendly shakes, bites, soups and drinks, says people are at risk of dehydration when calories are substantially restricted

Signs of Serious Issues Contact your doctor immediately if your fatigue is accompanied by any of the following "red flag" symptoms: Severe or persistent vomiting or diarrhoea Dizziness, light-headedness, or fainting A persistent rapid heart rate Confusion or difficulty concentrating Signs of severe dehydration (e.g., dark urine, no urination for 8+ hours) Medication Review Large-scale semaglutide trials show GI side effects (nausea, diarrhoea, vomiting, constipation) are most frequent in the first weeks post-injection but are usually mild and resolve with time and dietary management

Endometrial and menstrual blood mesenchymal stem/stromal cells: biological properties and clinical application