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Adults with a body mass index (BMI) of 30 or greater Adults with a BMI of 27 or greater who also have one weight-related condition, such as type 2 diabetes, high blood pressure, or high cholesterol Wegovy and Saxenda are also approved for the treatment of children age 12 and older

Recent studies reported that GLP-1R agonists, such as Val 8 -GLP-1(7-36), exendin-4 and liraglutide, attenuated A 1-42 -induced calcium overload by regulating intracellular calcium homeostasis in cortical or hippocampal pyramidal cells (173, 205, 206)

March 9, 2023

[DOI] [PMC free article] [PubMed] [Google Scholar] 52.Sposito A.C., Berwanger O., De Carvalho L.S.F., Saraiva J.F.K