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International Work Sharing - Access Consortium This initiative commenced in 2007 between the TGA, Health Canada, Swissmedic, and HSA of Singapore with the aim to increase regulatory reliance and information sharing, exchange knowledge and technical expertise, minimise duplication of regulatory effort, improve efficiency and resource allocation and ultimately ensure timely access for patients [19]

Cost Considerations and Access Orforglipron's potential to be manufactured at significantly lower cost than injectable peptide GLP-1s, due to its small-molecule chemistry amenable to standard pharmaceutical synthesis rather than complex peptide manufacturing, could reshape the economic field of GLP-1 therapy

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