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It adds that health professionals have a key role in identifying and managing the risks associated with unregistered GLP-1 products and should advise patients accordingly

[2] [3] Comparing Clinical Trials A randomized trial compared tirzepatide (10 mg or 15 mg) to semaglutide (1.7 mg or 2.4 mg) in adults with obesity but without type 2 diabetes over 72 weeks, showing tirzepatides superior weight loss and waist circumference reduction

Specifically, elevated levels of pro-inflammatory cytokines, such as IL-6 and TNF-, seem to trigger accelerated telomere shortening (Deo et al., 2020)

Antioxidants, such as thiol donors, inhibit NF-B-induced gene transcription 13